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Year : 2022  |  Volume : 10  |  Issue : 2  |  Page : 89-96

25-OH vitamin D3 level in tuberculosis: A cross-sectional study in a tertiary care center

1 Department of TB and Respiratory Medicine, IPGME&R and SSKM Hospital, Kolkata, West Bengal, India
2 ILS Hospitals, Howrah, West Bengal, India
3 Department of TB and Respiratory Medicine, Diamond Harbour Government Medical College and Hospital, West Bengal, India
4 Calcutta Skin Institute, Kolkata, West Bengal, India

Correspondence Address:
Rituparna Bose
Department of TB and Respiratory Medicine, Diamond Harbour Government Medical College, 210 Panch Masjid Road, Thakurpukur, Kolkata 700063, West Bengal
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jacp.jacp_30_22

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Abstract Introduction: The immunomodulatory role of 25-hydroxycholecalciferol (25-OH vitamin D3) has been under evaluation for a long time. As tuberculosis (TB) and MDR-TB continue to be global health problems, evaluation of the role of 25-OH vitamin D3 deficiency in TB and its relation with bacillary load may help us in formulating a preventive therapy for the disease. Aims and Objectives: To assess serum 25-OH vitamin D levels in patients suffering from TB for the first time and to find the relation between serum 25-OH vitamin D levels in patients with bacillary load in respiratory samples. Results: The serum 25-OH vitamin D level was analyzed for bacillary load in the respiratory specimen in this study, which revealed that as the serum 25-OH vitamin D level decreased, the bacillary load was found to increase in the respiratory specimen.

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