| ORIGINAL ARTICLE |
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| Year : 2022 | Volume
: 10
| Issue : 1 | Page : 22-25 |
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Do the symptoms affect SARS-CoV-2 RT-PCR results?
Melike Aloglu, Sevtap Gulgosteren, Sukran Atikcan
Department of Chest Diseases, Ankara Atatürk Chest Diseases and Thoracic Surgery Training and Research Hospital, University of Health Sciences, Ankara, Turkey
Correspondence Address:
Dr. Melike Aloglu
Department of Chest Diseases, Ankara Atatürk Chest Diseases and Thoracic Surgery Training and Research Hospital, University of Health Sciences, Pinarbasi Mahallesi, Sanatoryum Caddesi, Kecioren, Ankara 06280
Turkey
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jacp.jacp_37_21
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Background/aim: In December 2019, a novel coronavirus was defined as a pneumonia agent in China, spread all over the world, and caused severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; COVID-19) pandemic. The gold standard diagnostic procedure is SARS-CoV-2 reverse transcription-polymerase chain reaction (RT-PCR) examination, but might show false negativity. Aim of this retrospective study was to find whether symptoms of COVID-19 and SARS-CoV-2 RT-PCR positivity correlate or not, in pneumonia consistent with COVID-19. Materials and methods: Adult (≥18 years of age) patients hospitalized due to pneumonia and who had clinical and/or radiological findings (CO-RADS assessment was made) and symptoms consistent with COVID-19 were enrolled. Results: A total of 191 patients were enrolled, where 66 were females and 125 (65.4%) were males. Mean age was 59.72 ± 16.35 (range 19–89 years). Most common symptoms were dyspnea (61.8%), fever (35.6%), and cough (42.4%). Twenty-two of 191 patients had positive SARS-CoV-2 RT-PCR (11.5%). Dyspnea and fever tended to be more frequent in RT-PCR-positive cases, but in logistic regression analysis (LRA), showed no significance (P > 0.05). Conclusion: Dyspnea and fever tended to be more frequent in RT-PCR-positive cases, but in LRA, they showed no significance. Up to our results, symptoms do not matter for SARS-CoV-2 RT-PCR positivity in patients with pneumonia consistent with COVID-19.
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