REVIEW ARTICLE |
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Year : 2020 | Volume
: 8
| Issue : 2 | Page : 39-41 |
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COVID 19-lung interactions: the salient points for pulmonologist
Arup Halder1, Arpita Halder2
1 Woodlands Multispeciality Hospital, Kolkata, West Bengal, India 2 Department of Anatomy, College of Medicine & Sagore Datta Hospital, Kamarhati, Kolkata, West Bengal, India
Correspondence Address:
Dr. Arup Halder MD (TB & Respiratory Diseases), Consultant Pulmonologist, 1/16/2, Manick Tala Main Road, Kolkata 700054, West Bengal India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jacp.jacp_40_20
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The COVID 19 virus gains entry into body by docking to ACE2 receptors of lungs. Subsequently it deranges the balance in RAS and destabilizes oxidant-antioxidant systems. It leads to cytokine storm and endothelial dysfunction. Intially lung is compliant but patients may be hypoxic due to vasoplegia. Later typical full blown ARDS set in.
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