| REVIEW ARTICLE |
|
| Year : 2020 | Volume
: 8
| Issue : 2 | Page : 39-41 |
|
|
COVID 19-lung interactions: the salient points for pulmonologist
Arup Halder1, Arpita Halder2
1 Woodlands Multispeciality Hospital, Kolkata, West Bengal, India
2 Department of Anatomy, College of Medicine & Sagore Datta Hospital, Kamarhati, Kolkata, West Bengal, India
Correspondence Address:
Dr. Arup Halder
MD (TB & Respiratory Diseases), Consultant Pulmonologist, 1/16/2, Manick Tala Main Road, Kolkata 700054, West Bengal
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jacp.jacp_40_20
|
|
|
The COVID 19 virus gains entry into body by docking to ACE2 receptors of lungs. Subsequently it deranges the balance in RAS and destabilizes oxidant-antioxidant systems. It leads to cytokine storm and endothelial dysfunction. Intially lung is compliant but patients may be hypoxic due to vasoplegia. Later typical full blown ARDS set in.
|
|
|
|
| [FULL TEXT] [PDF]* |
|
 |
|
